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Partition observations into groups (default 10) by predicted risk and compare observed vs. expected event counts in each group. Good calibration means the two track each other across the risk spectrum.

Usage

hzr_deciles(object, time, groups = 10L, status = NULL, event_time = NULL)

Arguments

object

A fitted hazard object (with fit = TRUE).

time

Numeric scalar: the horizon at which predicted survival is used to rank subjects into risk groups (e.g. time = 12 ranks by 12-month predicted survival). It does not restrict the event/expected counts, which are accumulated over each subject's full follow-up.

groups

Integer: number of risk groups (default 10 for deciles).

status

Optional numeric vector of event indicators (1 = event, 0 = censored). If NULL (default), extracted from the fitted object's stored data.

event_time

Optional numeric vector of observed event/censoring times. If NULL (default), extracted from the fitted object.

Value

A data frame with one row per risk group and columns:

group

Integer group label (1 = lowest risk, ranked by predicted survival at time).

n

Number of observations in the group.

events

Observed event count in the group (all events over follow-up).

expected

Expected event count: the sum of each subject's predicted cumulative hazard at its own follow-up time.

observed_rate

Observed event rate (events / n).

expected_rate

Expected event rate (expected / n).

chi_sq

Chi-square contribution: (events - expected)^2 / expected.

p_value

Upper-tail p-value from the chi-square test for this group (1 df).

mean_survival

Mean predicted survival probability at the horizon in the group.

mean_cumhaz

Mean predicted cumulative hazard at follow-up in the group.

An attribute "overall" is attached with the overall chi-square statistic, degrees of freedom, and p-value.

Details

This reproduces the SAS deciles.hazard.sas macro. All subjects are ranked by predicted survival at the horizon time and split into equal-sized risk groups. Within each group the expected event count is the sum of each subject's predicted cumulative hazard at its own follow-up time, and the observed count is its number of events; under conservation of events the group totals sum to the total observed events. The horizon therefore only stratifies subjects into risk groups – it does not restrict or exclude any subject, and the expected/observed totals are independent of it.

See also

predict.hazard() for the prediction types used internally.

Examples

# \donttest{
data(avc)
avc <- na.omit(avc)
fit <- hazard(
  survival::Surv(int_dead, dead) ~ age + mal,
  data  = avc,
  dist  = "weibull",
  theta = c(mu = 0.01, nu = 0.5, beta_age = 0, beta_mal = 0),
  fit   = TRUE
)
cal <- hzr_deciles(fit, time = 120)
print(cal)
#> Decile-of-risk calibration (risk grouped at time = 120 )
#> 305 subjects, all included.
#> 10 groups, 68 observed events, 68.1 expected
#> 
#>  group  n events expected observed_rate expected_rate  chi_sq p_value
#>      1 31      2    0.949        0.0645        0.0306 1.16000  0.2810
#>      2 30      3    3.080        0.1000        0.1030 0.00187  0.9660
#>      3 31      5    4.900        0.1610        0.1580 0.00201  0.9640
#>      4 30      1    6.760        0.0333        0.2250 4.91000  0.0267
#>      5 31      4    7.330        0.1290        0.2360 1.51000  0.2190
#>      6 30      7    7.160        0.2330        0.2390 0.00353  0.9530
#>      7 31     12    6.600        0.3870        0.2130 4.41000  0.0357
#>      8 30     10    6.860        0.3330        0.2290 1.44000  0.2310
#>      9 31     11   12.300        0.3550        0.3970 0.14100  0.7070
#>     10 30     13   12.200        0.4330        0.4060 0.05720  0.8110
#>  mean_survival mean_cumhaz
#>          0.963      0.0306
#>          0.881      0.1030
#>          0.814      0.1580
#>          0.757      0.2250
#>          0.717      0.2360
#>          0.681      0.2390
#>          0.668      0.2130
#>          0.655      0.2290
#>          0.520      0.3970
#>          0.396      0.4060
#> 
#> Overall: chi-sq = 13.6 on 9 df, p = 0.136 
# }